Sucralfate CAS 54182-58-0 is an effective anti-ulcer medication that acts by protecting the ulcer surface and promoting ulcer healing.
Application: Sucralfate is used for the treatment of gastric ulcers and duodenal ulcers. It works by reducing acid production and inhibiting gastric proteases.
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Item |
Standard Regulation |
Test Result |
|
Appearance |
Appearance |
White or almost white powder |
Almost white powder |
Analysis |
Chlorides |
≤0.50% |
<0.50% |
Acid-neutralizing capacity |
≤14.0ml |
11.6ml |
|
Aluminum content |
16.5% ~18.5% |
17.8% |
|
Related substances |
(1) Individual unspecified impurity: not more than 0.05% |
Not detected |
|
(2) Impurity A: not more than 5.0% |
0.2% |
||
(3) Total impurities: not more than 5.0% |
0.2% |
||
Sucrose octasulfate content |
30.0% ~36.0% |
33.3% |
|
Residual solvent |
(1) Methanol: not more than 0.3% |
Not detected |
|
(2) Pyridine: not more than 0.02% |
Not detected |
||
(3) 2-methylpyridine: not more than 0.005% |
Not detected |
||
Microbial limit |
(1) TAMC ≤10³ cfu/g |
<1×101 cfu/g |
|
(2) TYMC ≤10² cfu/g |
<1×101 cfu/g |
||
(3) E.Coli: Not detectable |
Not detected |

Another Name: 54182-58-0; Sucrate; Sucralfato; Sukralfat; Carafate; Sucrose sulfate aluminum complex; Sucralfate API;
CAS No.: 54182-58-0
Physical characteristics: Odorless, nearly tasteless; hygroscopic. It is almost insoluble in water, ethanol, or chloroform. It readily dissolves in dilute hydrochloric acid or dilute sulfuric acid, and slightly dissolves in dilute nitric acid.
Molecular Formula: C11H60Al16O75S8
Molecular Weight: 2080.77000
MDL Number: MFCD00145339
Sucralfate (CAS 54182-58-0) offers several benefits as a medication for the treatment of gastrointestinal conditions. Some of the benefits of sucralfate include:
1. Ulcer Healing and Protection: Sucralfate forms a protective coating over ulcers in the gastrointestinal tract, including duodenal and gastric ulcers. This coating acts as a physical barrier, shielding the ulcers from the corrosive effects of stomach acid and digestive enzymes. It promotes the healing process by creating an environment that supports tissue repair.
2. Symptom Relief: By protecting the ulcerated areas, sucralfate can help alleviate symptoms associated with ulcers, such as pain, discomfort, and burning sensations. It provides relief by reducing the direct contact between the ulcers and stomach acid, allowing the damaged tissues to heal.
3. Minimal Systemic Absorption: Sucralfate is minimally absorbed into the bloodstream, meaning it mainly works locally in the gastrointestinal tract. This characteristic reduces the potential for systemic side effects and makes sucralfate well-tolerated by most patients.
4. Lack of Acid-Suppressing Effects: Unlike other medications used to treat ulcers, such as proton pump inhibitors (PPIs) or H2 receptor blockers, sucralfate does not directly inhibit acid production or acid secretion. It works by providing a physical barrier rather than reducing stomach acid levels. This can be advantageous for patients who do not require significant acid suppression or who may have contraindications or intolerances to acid-suppressing medications.
5. Flexibility in Administration: Sucralfate is available in tablet and suspension forms, providing flexibility in administration. It can be taken orally, typically on an empty stomach, allowing patients to incorporate it into their daily routine easily.
6. Few Drug Interactions: Sucralfate has minimal interactions with other medications. It does not affect the absorption or metabolism of many drugs, reducing the risk of drug interactions and allowing for safer co-administration with other medications.
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1. Payment term
TT, LC
2. Delivery date
Negotiable
3. Market
Middle East / Africa / Asia / South America / Europe
4. Sample
Available
5. Executive standards
CP, EP, IP
6. Qualification certificate
Registration "A" status of raw material packaging, Notification of Approval of marketing application for chemical API, WC, COPP, CEP, EUGMP, US DMF registration number, India Registration certificate, Brazil registration, Malaysia registration, etc.
7. Packaging size specification
Inner package: single-layer polyethylene bag and aluminum foil bag.
Outer package: fiber drum.
Packaging size: 25 kg/drum.
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Q: What is Sucralfate API?
Q: How does Sucralfate API work?
Q: What conditions can Sucralfate API treat?
Q: How is Sucralfate API administered?
Q: Are there any known side effects of Sucralfate API?
Q: Can Sucralfate API be used in certain patient populations?
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