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Sucralfate CAS 54182-58-0
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Product: Views:229Sucralfate CAS 54182-58-0 
Unit price: Negotiable
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Delivery date: Since the payment date Days delivery
Valid until: Long-term effective
Last updated: 2024-09-12 10:26
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Sucralfate CAS 54182-58-0 is an effective anti-ulcer medication that acts by protecting the ulcer surface and promoting ulcer healing.

Application: Sucralfate is used for the treatment of gastric ulcers and duodenal ulcers. It works by reducing acid production and inhibiting gastric proteases.

 

Item

Standard Regulation

Test Result

Appearance

Appearance

White or almost white powder

Almost white powder

Analysis

Chlorides

≤0.50%

<0.50%

Acid-neutralizing capacity

≤14.0ml

11.6ml

Aluminum content

16.5% ~18.5%

17.8%

Related substances

(1) Individual unspecified impurity: not more than 0.05%

Not detected

(2) Impurity A: not more than 5.0%

0.2%

(3) Total impurities: not more than 5.0%

0.2%

Sucrose octasulfate content

30.0% ~36.0%

33.3%

Residual solvent

(1) Methanol: not more than 0.3%

Not detected

(2) Pyridine: not more than 0.02%

Not detected

(3) 2-methylpyridine: not more than 0.005%

Not detected

Microbial limit

(1) TAMC ≤10³ cfu/g

<1×101 cfu/g

(2) TYMC ≤10² cfu/g

<1×101 cfu/g

(3) E.Coli: Not detectable

Not detected

Sucralfate CAS 54182-58-0
Product: Sucralfate 54182-58-0
Another Name: 54182-58-0; Sucrate; Sucralfato; Sukralfat; Carafate; Sucrose sulfate aluminum complex; Sucralfate API;
CAS No.: 54182-58-0
Physical characteristics: Odorless, nearly tasteless; hygroscopic. It is almost insoluble in water, ethanol, or chloroform. It readily dissolves in dilute hydrochloric acid or dilute sulfuric acid, and slightly dissolves in dilute nitric acid.
Molecular Formula: C11H60Al16O75S8
Molecular Weight: 2080.77000
MDL Number: MFCD00145339

Sucralfate (CAS 54182-58-0) offers several benefits as a medication for the treatment of gastrointestinal conditions. Some of the benefits of sucralfate include:

1. Ulcer Healing and Protection: Sucralfate forms a protective coating over ulcers in the gastrointestinal tract, including duodenal and gastric ulcers. This coating acts as a physical barrier, shielding the ulcers from the corrosive effects of stomach acid and digestive enzymes. It promotes the healing process by creating an environment that supports tissue repair.

2. Symptom Relief: By protecting the ulcerated areas, sucralfate can help alleviate symptoms associated with ulcers, such as pain, discomfort, and burning sensations. It provides relief by reducing the direct contact between the ulcers and stomach acid, allowing the damaged tissues to heal.

3. Minimal Systemic Absorption: Sucralfate is minimally absorbed into the bloodstream, meaning it mainly works locally in the gastrointestinal tract. This characteristic reduces the potential for systemic side effects and makes sucralfate well-tolerated by most patients.

4. Lack of Acid-Suppressing Effects: Unlike other medications used to treat ulcers, such as proton pump inhibitors (PPIs) or H2 receptor blockers, sucralfate does not directly inhibit acid production or acid secretion. It works by providing a physical barrier rather than reducing stomach acid levels. This can be advantageous for patients who do not require significant acid suppression or who may have contraindications or intolerances to acid-suppressing medications.

5. Flexibility in Administration: Sucralfate is available in tablet and suspension forms, providing flexibility in administration. It can be taken orally, typically on an empty stomach, allowing patients to incorporate it into their daily routine easily.

6. Few Drug Interactions: Sucralfate has minimal interactions with other medications. It does not affect the absorption or metabolism of many drugs, reducing the risk of drug interactions and allowing for safer co-administration with other medications.

 

1. Payment term

TT, LC

2. Delivery date

Negotiable

3. Market

Middle East / Africa / Asia / South America / Europe

4. Sample

Available
5. Executive standards
CP, EP, IP

6. Qualification certificate
Registration "A" status of raw material packaging, Notification of Approval of marketing application for chemical API, WC, COPP, CEP, EUGMP, US DMF registration number, India Registration certificate, Brazil registration, Malaysia registration, etc.

7. Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 25 kg/drum.

 

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Sucralfate API FAQ

 

Q: What is Sucralfate API?

A: Sucralfate API is an active pharmaceutical ingredient used in the formulation of medications for the treatment of gastrointestinal ulcers. It is a complex of aluminum hydroxide and sulfated sucrose.

Q: How does Sucralfate API work?

A: Sucralfate API works by forming a protective barrier over the ulcer surface. It adheres to the ulcer site, shielding it from stomach acid, enzymes, and bile salts. This barrier helps to promote healing by allowing the natural processes of tissue repair to occur.

Q: What conditions can Sucralfate API treat?

A: Sucralfate API is primarily used for the treatment of duodenal ulcers and gastric ulcers. It is also sometimes used for the management of gastroesophageal reflux disease (GERD) and stress ulcers.

Q: How is Sucralfate API administered?

A: Sucralfate API is typically administered orally in the form of tablets or suspensions. It is usually taken on an empty stomach, at least one hour before meals or two hours after meals. The specific dosage and duration of treatment will depend on the individual patient and the severity of the ulcer.

Q: Are there any known side effects of Sucralfate API?

A: Common side effects associated with Sucralfate API include constipation, dry mouth, indigestion, and nausea. These side effects are generally mild and transient. However, it is important to consult a healthcare professional if any unusual or severe side effects occur.

Q: Can Sucralfate API be used in certain patient populations?

A: Sucralfate API is generally considered safe for use in various patient populations, including adults and elderly individuals. However, caution should be exercised in patients with known allergies to aluminum or sulfates. It is important to consult with a healthcare professional for personalized advice based on individual patient characteristics and medical history.

 

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